CENTER OF MOLECULAR BIOLOGY AND PHARMACOGENETICS PUBLICATIONS

 

2016

 

Cuevas A, Fernandez C, Ferrada L, Zambrano T, Rosales A, Saavedra N, et al. HMGCR rs17671591 SNP Determines Lower Plasma LDL-C after Atorvastatin Therapy in Chilean Individuals. Basic & Clinical Pharmacology & Toxicology 2016;118(4):292-297.


Fuentes A, Ortiz J, Saavedra N, Salazar LA, Meneses C, Arriagada C. Reference gene selection for quantitative real-time PCR in Solanum lycopersicum L. inoculated with the mycorrhizal fungus Rhizophagus irregularis. Plant Physiology and Biochemistry 2016;101:124-131.


Muñoz, M. P.; Espinoza, E. G.; Nuñez, G. & Sanhueza, C. A. Disponibilidad de flúor en saliva y biofilms en escolares expuestos a leche o agua fluorurada. Int. J. Odontostomatology 2015; 9(3):393-398


Otzen T, Sanhueza A, Manterola C, Hetz M, Melnik T. Homicide in Chile: Trends 2000 - 2012 (vol 15, 312, 2015). Bmc Psychiatry 2016;16.


Riquelme I, Tapia O, Leal P, Sandoval A, Varga MG, Letelier P, et al. miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway. Cellular Oncology 2016;39(1):23-33.


Saavedra N, Cuevas A, Cavalcante MF, Dorr FA, Saavedra K, Zambrano T, et al. Polyphenols from Chilean Propolis and Pinocembrin Reduce MMP-9 Gene Expression and Activity in Activated Macrophages. Biomed Research International 2016.


Veloz JJ, Saavedra N, Alvear M, Zambrano T, Barrientos L, Salazar LA. Polyphenol-Rich Extract from Propolis Reduces the Expression and Activity of Streptococcus mutans Glucosyltransferases at Subinhibitory Concentrations. Biomed Research International 2016


Zambrano T, Hirata RDC, Hirata MH, Cerda A, Salazar LA. Altered microRNome Profiling in Statin-Induced HepG2 Cells: A Pilot Study Identifying Potential new Biomarkers Involved in Lipid-Lowering Treatment. Cardiovascular Drugs and Therapy 2015;29(6):509-518.

 

2015

Bizama C, Garcia P, Espinoza JA, Weber H, Leal P, Nervi B, et al. Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy. Cancer Treatment Reviews 2015;41(3):222-234.


Caamano J, Musante E, Contreras M, Ulloa H, Reyes C, Inaipil V, et al. Frequency and Specificity of Red Blood Cell Alloimmunization in Chilean Transfused Patients. Transfusion Medicine and Hemotherapy 2015;42(1):4-7.


Calaf GM, Zepeda AB, Castillo RL, Figueroa CA, Arias C, Figueroa E, et al. Molecular aspects of breast cancer resistance to drugs (Review). International Journal of Oncology 2015;47(2):437-445.


Castellanos ER, Seron P, Gisbert JP, Cosp XB. Endoscopic injection of cyanoacrylate glue versus other endoscopic procedures for acute bleeding gastric varices in people with portal hypertension. Cochrane Database of Systematic Reviews 2015(5).


Cerda A, Fajardo CM, Basso RG, Hirata MH, Dominguez R, Hirata C. Role of microRNAs 221/222 on Statin Induced Nitric Oxide Release in Human Endothelial Cells. Arquivos Brasileiros De Cardiologia 2015;104(3):195-200.


Cerda A, Rodrigues AC, Alves C, Genvigir FD, Fajardo CM, Dorea EL, et al. Modulation of Adhesion Molecules by Cholesterol-Lowering Therapy in Mononuclear Cells from Hypercholesterolemic Patients. Cardiovascular Therapeutics 2015;33(4):168-176.


Cuevas A, Saavedra N, Rudnicki M, Abdalla DSP, Salazar LA. ERK1/2 and HIF1 alpha Are Involved in Antiangiogenic Effect of Polyphenols-Enriched Fraction from Chilean Propolis. Evidence-Based Complementary and Alternative Medicine 2015.


Castro-Avila AC, Seron P, Fan E, Gaete M, Mickan S. Effect of Early Rehabilitation during Intensive Care Unit Stay on Functional Status: Systematic Review and Meta-Analysis. Plos One 2015;10(7).


Cerda A, Fajardo CM, Basso RG, Hirata MH, Dominguez R, Hirata C. Role of microRNAs 221/222 on Statin Induced Nitric Oxide Release in Human Endothelial Cells. Arquivos Brasileiros De Cardiologia 2015;104(3):195-200.


Guzman N, Larama G, Avila A, Salazar LA. Three novel variants in the coagulation factor V gene associated with deep venous thrombosis in Chilean patients with Amerindian ethnic background. Clinica Chimica Acta 2015;444:24-28


Hernandez AH, Curi R, Salazar LA. Selection of reference genes for expression analyses in liver of rats with impaired glucose metabolism. International Journal of Clinical and Experimental Pathology 2015;8(4):3946-3954.


Jaramillo PC, Fuentes K, Cortes C, Cisternas C, Salazar LA. Interaction between Rs671 Polymorphism of the ALDH2 Gene and Alcohol Consumption in Chilean Individuals. International Journal of Morphology 2015;33(1):68-72.


Lagos J, Zambrano T, Rosales A, Salazar LA. APOE Polymorphisms Contribute to Reduced Atorvastatin Response in Chilean Amerindian Subjects. International Journal of Molecular Sciences 2015;16(4):7890-7899.


Lanas F, Seron P, Saavedra N, Ruedlinger J, Salazar L. Genetic and Non-Genetic Determinants of Circulating Levels of Adiponectin in a Cohort of Chilean Subjects. Molecular Diagnosis & Therapy 2015;19(4):197-204.


Rodriguez-Niklitschek CA, Oporto GH, Garay I, Salazar LA. Clinical, imaging and genetic analysis of double bilateral radix entomolaris. Folia Morphologica 2015;74(1):127-132.


Seron P, Lanas F, Rios E, Bonfill X, Alonso-Coello P. Evaluation of the Quality of Clinical Guidelines for Cardiac Rehabilitation A CRITICAL REVIEW. Journal of Cardiopulmonary Rehabilitation and Prevention 2015;35(1):1-12


Seron P, Pardo H, Lanas F. Cochrane corner: exercise for people with high cardiovascular risk. Heart 2015;101(9):663-664.


Veloz JJ, Saavedra N, Lillo A, Alvear M, Barrientos L, Salazar LA. Antibiofilm Activity of Chilean Propolis on Streptococcus mutans Is Influenced by the Year of Collection. Biomed Research International 2015.


Zambrano T, Saavedra N, Lanas F, Caamano J, Salazar LA. Efficacy of Ezetimibe Is Not Related to NPC1L1 Gene Polymorphisms in a Pilot Study of Chilean Hypercholesterolemic Subjects. Molecular Diagnosis & Therapy 2015;19(1):45-52.


Zambrano T, Hirata MH, Cerda A, Dorea EL, Pinto GA, Gusukuma MC, et al. Impact of 3 ' UTR genetic variants in PCSK9 and LDLR genes on plasma lipid traits and response to atorvastatin in Brazilian subjects: a pilot study. International Journal of Clinical and Experimental Medicine 2015;8(4):5978-5988.

 

2014

Anderson JM; A Cerda; MH Hirata; AC Rodrigues; EL Dorea; MMS Bernik; MC Bertolami, et al. Influence of PCSK9 polymorphisms on plasma lipids and response to atorvastatin treatment in Brazilian subjects. Journal of Clinical Lipidology 2014 8(3);256-264


Beltran V; M Silva; M Padilla; E Aillapan; A Sanhueza; M Cantin; R Fuentes. Morphological Patterns of Gingival Recession in Adult Chilean Population. International Journal of Morphology 2013 31(4);1365-1370.


Brebi P; L Maldonado; MG Noordhuis; C Ili; P Leal; P Garcia; M Brait, et al. Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population. Epigenetics 2014 9(2);308-317


Cuevas A; N Saavedra; MF Cavalcante; LA Salazar; DSP Abdalla. Identification of microRNAs involved in the modulation of pro-angiogenic factors in atherosclerosis by a polyphenol-rich extract from propolis. Archives of Biochemistry and Biophysics 2014 557;28-35


de Oliveira R; A Cerda; FD Genvigir; MF Sampaio; D Armaganijan; MMS Bernik; EL Dorea, et al. Leptin receptor gene polymorphisms are associated with adiposity and metabolic alterations in Brazilian individuals. Arquivos Brasileiros De Endocrinologia E Metabologia 2013 57(9);677-684


Herrera-Bravo J; E Montiel-Eulefi; T Glaser; M Garces; P Leal; AH Ulrich. In vitro Translocation Cytoplasm/nucleus of Embryonic Transcription Factor OCT-4 in Perivascular Cells Suggests that Aorta as a Niche of Quiescent Adult Stem Cells. International Journal of Morphology 2013 31(4);1430-1438


Lagos J; T Zambrano; A Rosales; LA Salazar. Influence of SREBP-2 and SCAP Gene Polymorphisms on Lipid-Lowering Response to Atorvastatin in a Cohort of Chilean Subjects with Amerindian Background. Molecular Diagnosis & Therapy 2014 18(4);435-443


Lanas F; P Seron; S Munoz; P Margozzini; T Puig. Waist to high ratio better identified cardiovascular risk factors and increased cardiovascular risk in a chilean survey. European Heart Journal 2014 35;559-559


Lanas F; P Seron; T Puig. Cardiovascular risk factors among males in 1989 and 2011-12 in a southern Chilean city. Revista Medica De Chile 2014 142(4);467-474


Lear SA; K Teo; D Gasevic; XH Zhang; PP Poirier; S Rangarajan; P Seron, et al. The association between ownership of common household devices and obesity and diabetes in high, middle and low income countries. Canadian Medical Association Journal 2014 186(4);258-266


Leiva V; E Rojas; M Galea; A Sanhueza. Diagnostics in Birnbaum-Saunders accelerated life models with an application to fatigue data. Applied Stochastic Models in Business and Industry 2014 30(2);115-131


Letelier P; P Garcia; P Leal; C Ili; K Buchegger; I Riquelme; A Sandoval, et al. Immunohistochemical Expression of Vascular Endothelial Growth Factor A in Advanced Gallbladder Carcinoma. Applied Immunohistochemistry & Molecular Morphology 2014 22(7);530-536.


Letelier P; P Garcia; P Leal; H Alvarez; C Ili; J Lopez; J Castillo, et al. miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer. International Journal of Clinical and Experimental Pathology 2014 7(5);1849-1867


Montiel-Eulefi E; F Jara; C Toro; M Garces; P Leal. Cytotoxic Effect of Double Emulsion (W/O/W) CuSO4 Loaded PLA Nanoparticles on MKN-45 Gastric Adenocarcinoma Cell Line. International Journal of Morphology 2014 32(1);61-69


Rios E; P Seron; F Lanas; X Bonfill; EMM Quigley; P Alonso-Coello. Evaluation of the quality of clinical practice guidelines for the management of esophageal or gastric variceal bleeding. European Journal of Gastroenterology & Hepatology 2014 26(4);422-431


Sanhueza A; T Otzen; C Manterola; N Araneda. Statistical Approaches for Analyzing a Continuous Outcome in Experimental Studies. International Journal of Morphology 2014 32(1);339-350


Otzen T; A Sanhueza; C Manterola; JA Escamilla-Cejudo. Trends in suicide mortality in Chile from 1998 to 2011. Revista Médica De Chile 2014 142(3);305-313
Tapia O; I Riquelme; P Leal; A Sandoval; S Aedo; H Weber; P Letelier, et al. The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance. Virchows Archiv 2014 465(1);25-33


Zepeda AB; CA Figueroa; DSP Abdalla; AQ Maranhao; PH Ulloa; A Pessoa; JG Farias. Biomarkers to evaluate the effects of temperature and methanol on recombinant Pichia pastoris. Brazilian Journal of Microbiology 2014 45(2);475-483


Zepeda AB; CA Figueroa; DSP Abdalla; AQ Maranhao; PH Ulloa; A Pessoa; JG Farias. HSF-1, HIF-1 and HSP90 expression on recombinant Pichia pas of is under fed-batch fermentation. Brazilian Journal of Microbiology 2014 45(2);485-490

 

2013

Barrientos L; Herrera CL; Montenegro G; Ortega X; Veloz J; Alvear M; Cuevas A; Saavedra N; Salazar LA. Chemical and botanical characterization of Chilean propolis and biological activity on cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus. Brazilian Journal of Microbiology 2013, 44(2); 577-585.


Cuevas A; Saavedra N; Salazar LA; Abdalla DS. Modulation of immune function by polyphenols: possible contribution of epigenetic factors. Nutrients 2013, 5(7); 2314-2332.


López-Jaramillo P; Sánchez RA; Díaz M; Cobos L; Bryce A; Parra-Carrillo JZ; Lizcano F; Lanas F; Sinay I; Sierra ID; Peñaherrera E; Benderky M; Schmid H; Botero R; Urina M; Lara J; Foos MC; Márquez G; Harrap S; Ramírez AJ; Zanchetti A; Grupo de Expertos de Latinoamérica. Latin American consensus on hypertension in patients with diabetes type 2 and metabolic syndrome. Clinica e Investigación en Arteriosclerosis 2013 (in press).


Dehghan M; Martinez S; Zhang X; Seron P; Lanas F; Islam S; Merchant AT. Relative validity of an FFQ to estimate daily food and nutrient intakes for Chilean adults. Public Health Nutrition 2013, 16(10); 1782-1788.


Castro P; Verdejo H; Altamirano R; Downey P; Vukasovic JL; Sepúlveda L; Lanas F; Bilbao P; Pacheco R; Rossel V; grupo ICARO. Deterioration of kidney function as a risk factor for mortality among patients hospitalized for heart failure. Revista Médica de Chile 2013, 141(8); 995-1002.


Nazzal C; Lanas F; Garmendia ML; Bugueño C; Mercadal E; Garcés E; Yovaniniz P; Sanhueza P. Universal health coverage and accomplishment of secondary prevention goals among patients with acute myocardial infarction. Revista Médica de Chile 2013, 141(8); 977-986.


Corsi DJ; Subramanian SV; Chow CK; McKee M; Chifamba J; Dagenais G; Diaz R; Iqbal R; Kelishadi R; Kruger A; Lanas F; López-Jaramilo P; Mony P; Mohan V; Avezum A; Oguz A; Rahman MO; Rosengren A; Szuba A; Li W; Yusoff K; Yusufali A; Rangarajan S; Teo K; Yusuf S. Prospective Urban Rural Epidemiology (PURE) study: Baseline characteristics of the household sample and comparative analyses with national data in 17 countries. American Heart Journal 2013, 166(4); 636-646.


Garcia DA; Wallentin L; Lopes RD; Thomas L; Alexander JH; Hylek EM; Ansell J; Hanna M; Lanas F; Flaker G; Commerford P; Xavier D; Vinereanu D; Yang H; Granger CB. Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial. American Heart Journal 2013, 166(3): 549-558


Chow CK; Teo KK; Rangarajan S; Islam S; Gupta R; Avezum A; Bahonar A; Chifamba J; Dagenais G; Diaz R; Kazmi K; Lanas F; Wei L; Lopez-Jaramillo P; Fanghong L; Ismail NH; Puoane T; Rosengren A; Szuba A; Temizhan A; Wielgosz A; Yusuf R; Yusufali A; McKee M; Liu L; Mony P; Yusuf S; PURE (Prospective Urban Rural Epidemiology) Study investigators. Prevalence, Awareness, Treatment, and Control of Hypertension in Rural and Urban Communities in High-, Middle-, and Low-Income Countries. JAMA-Journal of the American Medical Association 2013, 310(9); 959-968.


Wallentin L; Lopes RD; Hanna M; Thomas L; Hellkamp A; Nepal S; Hylek EM; Al-Khatib SM; Alexander JH; Alings M; Amerena J; Ansell J; Aylward P; Bartunek J; Commerford P; De Caterina R; Erol C; Harjola VP; Held C; Horowitz JD; Huber K; Husted S; Keltai M; Lanas F; Lisheng L; McMurray JJ; Oh BH; Rosenqvist M; Ruzyllo W; Steg PG; Vinereanu D; Xavier D; Granger CB; Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Investigators. Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation. Circulation 2013, 127(22); 2166-2176.


Teo K; Lear S; Islam S; Mony P; Dehghan M; Li W; Rosengren A; Lopez-Jaramillo P; Diaz R; Oliveira G; Miskan M; Rangarajan S; Iqbal R; Ilow R; Puone T; Bahonar A; Gulec S; Darwish EA; Lanas F; Vijaykumar K; Rahman O; Chifamba J; Hou Y; Li N; Yusuf S; PURE Investigators. Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries The Prospective Urban Rural Epidemiology (PURE) Study. JAMA-Journal of the American Medical Association 2013, 309(15); 1613-1621.


Lip GY; Connolly S; Yusuf S; Shestakovska O; Flaker G; Hart R; Lanas F; Xavier D; Eikelboom J; ERROES Investigators. Modification of outcomes with aspirin or apixaban in relation to CHADS(2) and CHA(2)DS(2)-VASc scores in patients with atrial fibrillation: a secondary analysis of the AVERROES study. Circulation. Arrhythmia and Electrophysiology 2013, 6(1); 31-38.


Neira V; Potthoff M; Quininir L; Lopez G; Stockins B; Castillo C; Lanas F. Achievement of cardiovascular prevention goals, pharmacologic prescription and major cardiovascular events among patients with coronary disease. Revista Médica de Chile 2013, 141(7); 870-878.


Romo E; Weinacker D; Zepeda AB; Figueroa CA; Chavez-Crooker P; Farías JG. Bacterial consortium for copper extraction from sulphide ore consisting mainly of chalcopyrite. Brazilian Journal of Microbiology 2013, 44(2); 523-528.


Rabert C; Weinacker D; Pessoa A; Farías JG. Recombinants proteins for industrial uses: utilization of Pichia pastoris expression system. Brazilian Journal of Microbiology 2013, 44(2); 351-356.


Castillo RL; Arias C; Farías JG. Omega 3 chronic supplementation attenuates myocardial ischaemia-reperfusion injury through reinforcement of antioxidant defense system in rats. Cell Biochemistry and Function 2013.


Zepeda AB; Calaf GM; Figueroa CA; Farías JG. Blueberries prevent the effect of intermittent hypobaric hypoxia in rat epididymis. Andrología 2013.
Zepeda AB; Pessoa A; Castillo RL; Figueroa CA; Pulgar VM; Farías JG. Cellular and molecular mechanisms in the hypoxic tissue: role of HIF-1 and ROS. Cell Biochemistry and Function 2013, 31(6); 451-459.


Farias JG; Jiménez D; Osorio J; Zepeda AB; Figueroa CA; Pulgar VM. Acclimatization to chronic intermittent hypoxia in mine workers: a challenge to mountain medicine in Chile. Biological Research 2013, 46(1); 59-67.


Pino JA; Osses N; Oyarzun D; Farias JG; Moreno RD; Reyes JG. Differential effects of temperature on reactive oxygen/nitrogen species production in rat pachytene spermatocytes and round spermatids. Reproduction 2013, 145(2); 203-212.


Valdes PR; Alarcón AM; Muñoz SR. Evaluation of Informed Choice for contraceptive methods among women attending a family planning program: conceptual development; a case study in Chile. Journal of Clinical Epidemiology 2013, 66(3); 302-307.

 

Silva JR; Capurro G; Saumann MP; Slachevsky A. Problematic eating behaviors and nutritional status in 7 to 12 year-old Chilean children. International Journal of Clinical and Health Psychology 2013, 13(1); 32-39.


Fierro R; Leiva V; Ruggeri F; Sanhueza A. On a Birnbaum-Saunders distribution arising from a non-homogeneous Poisson process. Statistics & Probability Letters 2013; 83(4); 1233-1239.


Moraga J; Burgos ME; Manterola C; Sanhueza A; Cartes-Velasquez R; Urrutia S; MMIC Group. Validation of a scale for assessing methodological quality of therapy studies. Pilot study. Revista Chilena de Cirugía 2013; 65(3); 222-227.


Oporto GH; Saavedra R; Soto PCC; Fuentes R. Double Root Anatomical Variations in a Single Patient: Endodontic Treatment and Rehabilitation of a Three-rooted First Premolar. Case Report. International Journal of Morphology 2013, 31(1); 45-49.


Jorquera MA; Saavedra N; Maruyama F; Richardson AE; Crowley DE; Catrilaf RD; Henriquez EJ, de la Luz Mora M. Phytate addition to soil induces changes in the abundance and expression of Bacillus beta-propeller phytase genes in the rhizosphere. FEMS Microbiology Ecology 2013, 83(2): 352-360.


McMurray JJ; Packer M; Desai AS; Gong J; Lefkowitz MP; Rizkala AR; Rouleau J; Shi VC; Solomon SD; Swedberg K; Zile MR; PARADIGM-HF Committees and Investigators. Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF). Eur J Heart Fail. 2013, 15(9); 1062-1073.


Lamy A; Devereaux PJ; Prabhakaran D; Taggart DP; Hu S; Paolasso E; Straka Z; Piegas LS; Akar AR; Jain AR; Noiseux N; Padmanabhan C; Bahamondes JC; Novick RJ; Vaijyanath P; Reddy SK; Tao L; Olavegogeascoechea PA; Airan B; Sulling TA; Whitlock RP; Ou Y; Pogue J; Chrolavicius S; Yusuf S; CORONARY Investigators. Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year. N Engl J Med. 2013, 368(13); 1179-1188.

 

2012

Rosales A; Alvear M; Cuevas A; Saavedra N; Zambrano T; Salazar LA. Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia. Clinica Chimica Acta 2012, 413(3-4); 495-501.


Daleprane JB; Freitas Vda S; Pacheco A; Rudnicki M; Faine LA; Dörr FA; Ikegaki M; Salazar LA; Ong TP; Abdalla DS. Anti-atherogenic and anti-angiogenic activities of polyphenols from propolis. Journal of Nutritional Biochemistry 2012, 23(6); 557-66.


Caamaño JM; N Saavedra; C Wulff; LA Salazar. Therapeutic response to ezetimibe in C57BL/6 mice is mediated by changes in NPC1L1, ABCG5 and ABCG8 expression in the enterocyte. International Journal of Morphology 2012, 30(2); 531-540.


Caamaño JM; N Saavedra; T Zambrano; F Lanas; LA Salazar. Effect of Five Single Nucleotide Polymorphisms of ABCG5 and ABCG8 Genes on Ezetimibe Lipid-Lowering Response. International Journal of Morphology 2012, 30(2); 688-695.


Curifuta M; J Vidal; J Sanchez-Venegas; A Contreras; LA Salazar; M Alvear. The in vitro antifungal evaluation of a commercial extract of Chilean propolis against six fungi of agricultural importance. Ciencia e Investigacion Agraria 2012, 39(2); 347-359.


Hernandez A; R Curi; LA Salazar. Repression of Ppargc1a Gene in Liver of Hyperglycemic Rats Induced with High Fat Diet Combined with Streptozotocin. International Journal of Morphology 2012, 30(2); 643-650.


Farias JG; AB Zepeda; GM Calaf. Melatonin Protects the Heart, Lungs and Kidneys from Oxidative Stress under Intermittent Hypobaric Hypoxia in Rats. Biological Research 2012, 45(1); 81-85.


Athayde E; C Azevedo; V Leiva; A Sanhueza. About Birnbaum-Saunders Distributions Based on the Johnson System. Communications in Statistics-Theory and Methods 2012, 41(11); 2061-2079.


Garcia N; A Sanhueza; M Cantin; R Fuentes. Evaluation of Cervical Posture of Adolescent Subjects in Skeletal Class I, II, and III. International Journal of Morphology 2012, 30(2); 405-410.


Hohnloser SH; Z Hijazi; L Thomas; JH Alexander; J Amerena; M Hanna; M Keltai, et al. Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial. European Heart Journal 2012, 33(22); 2821-2830.


Lamy A; PJ Devereaux; D Prabhakaran; SS Hu; LS Piegas; Z Straka; E Paolasso, et al. Rationale and design of The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study: A large international randomized trial in cardiac surgery. American Heart Journal 2012, 163(1); 1-6.


Philco P; P Seron; S Munoz; P Navia; F Lanas. Risk factors for metabolic syndrome in a case control study in Temuco, Chile. Revista Medica de Chile 2012, 140(3); 334-339.


Anand SS; GR Dagenais; V Mohan; R Diaz; J Probstfield; R Freeman; J Shaw, et al. Glucose levels are associated with cardiovascular disease and death in an international cohort of normal glycaemic and dysglycaemic men and women: the EpiDREAM cohort study. European Journal of Preventive Cardiology 2012, 19(4); 755-764.


Oporto G; Lagos J; Bornhardt T; Fuentes R; Salazar LA. Are there Genetic Factors Involved in Bruxism?. International Journal of Odontostomatology 2012, 6(3); 249-254.


Zepeda AB; Figueroa CA; Calaf GM; Farías JG. Male reproductive system and antioxidants in oxidative stress induced by hypobaric hypoxia. Andrologia 2012 [Epub ahead of print].


Reyes JG; Farias JG; Henríquez-Olavarrieta S; Madrid E; Parraga M; Zepeda AB; Moreno RD. The hypoxic testicle: physiology and pathophysiology. Oxidative Medicine Cellular Longevity 2012, 2012; 929285.


ORIGIN Trial Investigators; Gerstein HC; Bosch J; Dagenais GR; Díaz R; Jung H; Maggioni AP; Pogue J; Probstfield J; Ramachandran A; Riddle MC; Rydén LE; Yusuf S. Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med. 2012, 367(4); 319-28.


ORIGIN Trial Investigators; Bosch J; Gerstein HC; Dagenais GR; Díaz R; Dyal L; Jung H; Maggiono AP; Probstfield J; Ramachandran A; Riddle MC; Rydén LE; Yusuf S. n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med. 2012, 367(4); 309-318.


Easton JD; Lopes RD; Bahit MC; Wojdyla DM; Granger CB; Wallentin L; Alings M; Goto S; Lewis BS; Rosenqvist M; Hanna M; Mohan P; Alexander JH; Diener HC; ARISTOTLE Committees and Investigators. Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial. Lancet Neurol. 2012, 11(6); 503-511.


Lamy A; Devereaux PJ; Prabhakaran D; Taggart DP; Hu S; Paolasso E; Straka Z; Piegas LS; Akar AR; Jain AR; Noiseux N; Padmanabhan C; Bahamondes JC; Novick RJ; Vaijyanath P; Reddy S; Tao L; Olavegogeascoechea PA; Airan B; Sulling TA; Whitlock RP; Ou Y; Ng J; Chrolavicius S; Yusuf S; CORONARY Investigators. Off-pump or on-pump coronary-artery bypass grafting at 30 days. N Engl J Med. 2012, 366(16); 1489-97.


Hankey GJ; Patel MR; Stevens SR; Becker RC; Breithardt G; Carolei A; Diener HC; Donnan GA; Halperin JL; Mahaffey KW; Mas JL; Massaro A; Norrving B; Nessel CC; Paolini JF; Roine RO; Singer DE; Wong L; Califf RM; Fox KA; Hacke W; ROCKET AF Steering Committee Investigators. Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF. Lancet Neurol. 2012, 11(4); 315-322.


Diener HC; Eikelboom J; Connolly SJ; Joyner CD; Hart RG; Lip GY; O'Donnell M; Hohnloser SH; Hankey GJ; Shestakovska O; Yusuf S; AVERROES Steering Committee and Investigators. Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial. Lancet Neurol. 2012, 11(3); 225-231.


Büller HR; Gallus AS; Pillion G; Prins MH; Raskob GE; Cassiopea Investigators. Enoxaparin followed by once-weekly idrabiotaparinux versus enoxaparin plus warfarin for patients with acute symptomatic pulmonary embolism: a randomised, double-blind, double-dummy, non-inferiority trial. Lancet. 2012, 379(9811); 123-129.


Büller HR; Gallus AS; Pillion G; Prins MH; Raskob GE; Cassiopea Investigators. Enoxaparin followed by once-weekly idrabiotaparinux versus enoxaparin plus warfarin for patients with acute symptomatic pulmonary embolism: a randomised, double-blind, double-dummy, non-inferiority trial. Lancet. 2012, 379(9811); 123-129.


Punthakee Z; Bosch J; Dagenais G; Diaz R; Holman R; Probstfield J; Ramachandran A; Riddle M; Rydén LE; Zinman B; Afzal R; Yusuf S; Gerstein H; TIDE Trial Investigators. Design, history and results of the Thiazolidinedione Intervention with vitamin D Evaluation (TIDE) randomised controlled trial. Diabetologia. 2012, 55(1); 36-45.

 

2011

Esparza Y; Huaiquil A; Neira L; Leyton A; Rubilar M; Salazar L; Shene C. Optimization of Process Conditions for the Production of a Prolyl-endopeptidase by Aspergillus niger ATCC 11414 in Solid State Fermentation. Food Science and Biotechnology 2011, 20(5); 1323-1330.


Marquez JL; Hirabara SM; Fiamoncini J; Hatanaka E; Alba-Loureiro TC; de Lima-Salgado TM; Curi R; Salazar LA. Akt Expression is Diminished by Physical Inactivity in Early Stages of Development in Soleus Muscle of Rats. International Journal of Morphology 2011, 29(1); 256-267.


Montiel-Eulefi E; Diaz LB; Leal P; Roa JC; Risopatron J; Salazar LA; Romero F; Sanchez R. Pericytes: New Approaches in Regenerative Therapy, Cerebrovascular Pathology and Cancer. International Journal of Morphology 2011, 29(3); 769-781.


Saavedra N; Barrientos L; Herrera CL; Alvear M; Montenegro G; Salazar LA. Effect of Chilean propolis on cariogenic bacteria Lactobacillus fermentum. Ciencia e Investigacion Agraria 2011, 38(1); 117-125.


Pacheco A; Daleprane JB; Freitas VS; Ferderbar S; Hirabara S; Cuevas A; Saavedra N; Curi R; Abdalla DSP; Salazar LA. Effect of Chilean Propolis on Glucose Metabolism in Diabetic Mice. International Journal of Morphology 2011, 29(3); 754-761.


Sanhueza J; Herrera CL; Salazar LA; Silva J. CRF-BP and SLC6A4 gene polymorphisms among restrained eaters. Revista Medica de Chile 2011, 139(10); 1261-1268.


Roig A; Henriquez J; Alvear M; Salazar LA. Morphometric Analysis of Odontoblasts Number in Direct Capping with Calcium Hydroxide and Propolis in Dogs. International Journal of Morphology 2011, 29(3); 799-805.


Rosales A; Pacheco A; Cuevas A; Saavedra N; Zambrano T; Lanas F; Salazar LA. Frequency of Common Variants in Genes Involved in Lipid-Lowering Response to Statins in Chilean Subjects with Hypercholesterolemia. International Journal of Morphology 2011, 29(4); 1296-1302.


Connolly S; Camm AJ; Halperin JL; Joyner C; Alings M; Amerena J; Atar D; Avezum A; Blomström P; Borggrefe M; Budaj A; Chen SA; Ching CK; Commerford P; Dans A; Davy JM; Delacrétaz E; Di Pasquale G; Diaz R; Dorian P; Flaker G; Golitsyn S; Gonzalez-Hermosillo A; Granger CB; Heidbüchel H; Kautzner J; Kim JS; Lanas F; Lewis BS; Merino JL; Morillo C; Murin J; Narasimhan C; Paolasso E; Parkhomenko A; Peters NS; Sim KH; Stiles MK; Tanomsup S; Toivonen L; Tomcsányi J; Torp-Pedersen C; Tse HF; Vardas P; Vinereanu D; Xavier D; Zhu J; Zhu JR; Baret-Cormel L; Weinling E; Pharm.D.; Staiger C; Yusuf S; Chrolavicius S; Afzal R; Hohnloser SH; PALLAS Investigators. Dronedarone in High-Risk Permanent Atrial Fibrillation. N Engl J Med 2011, 365; 2268-2276.


Connolly SJ; Eikelboom J; Joyner C; Diener HC; Hart R; Golitsyn S; Flaker G; Avezum A; Hohnloser SH; Diaz R; Talajic M; Zhu J; Pais P; Budaj A; Parkhomenko A; Jansky P; Commerford P; Tan RS; Sim KH; Lewis BS; Van Mieghem W; Lip GY; Kim JH; Lanas-Zanetti F; Gonzalez-Hermosillo A; Dans AL; Munawar M; O'Donnell M; Lawrence J; Lewis G; Afzal R; Yusuf S; AVERROES Steering Committee and Investigators. Apixaban in patients with atrial fibrillation. N Engl J Med. 2011, 364(9); 806-817.


Balakrishnan N; Kundu GD, Leiva V; Sanhueza A. On some mixture models based on the Birnbaum-Saunders distribution and associated inference. Journal of Statistical Planning and Inference 2011, 141(7); 2175-2190.


Burgos ME, Manterola C; Sanhueza A. Construction of a scale to assess methodological quality of diagnostic tests articles. Revista Chilena de Cirugia 2011, 63(5); 493-497.


Castillo NO; Gomez HW, Leiva V; Sanhueza A. On the Fernandez-Steel distribution: Inference and application. Computational Statistics & Data Analysis 2011, 55(11); 2951-2961.


Losada H; Manterola C, Pineda V; Vial M; Sanhueza A; M. M. I. Grp. Methodological quality in prognostic papers (scale MinCir Pr). Revista Chilena de Cirugia 2011, 63(6); 579-584.


Raposo A; Monsalves MJ; Aravena P; Sanhueza A. Prevalence of Oral Mucosal Lesions at the Hernan Henriquez Aravena Hospital of Temuco. International Journal of Morphology 2011, 29(2); 622-627.


Riquelme M; Leiva V; Galea M; Sanhueza A. Influence diagnostics on the coefficient of variation of elliptically contoured distributions. Journal of Applied Statistics 2011, 38(3); 513-532.


Sanhueza A; Leiva V; Lopez-Kleine L. On the Student-t Mixture Inverse Gaussian Model with an Application to Protein Production. Revista Colombiana de Estadistica 2011, 34(1); 177-195.


Varas V; Fernandez RF; Cortes AB Campos AS. Relationship between Levels of Third Molar Inclusion and Physical Anthropometric Indices of the Mandible in the Atacameno and Aymara Ethnic Groups of Northern Chile. International Journal of Morphology 2011, 29(2); 446-454.


Rescorla LA; Achenbach TM; Ivanova MY; Harder VS; Otten L; Bilenberg N; Bjarnadottir G; Capron C; De Pauw SS; Dias P; Dobrean A; Döpfner M; Duyme M; Eapen V; Erol N; Esmaeili EM; Ezpeleta L; Frigerio A; Fung DS; Gonçalves M; Guðmundsson H; Jeng SF; Jusiené R; Ah Kim Y; Kristensen S; Liu J; Lecannelier F; Leung PW; Machado BC; Montirosso R; Ja Oh K; Ooi YP; Plück J; Pomalima R; Pranvera J; Schmeck K; Shahini M; Silva JR; Simsek Z; Sourander A; Valverde J; van der Ende J; Van Leeuwen KG; Wu YT; Yurdusen S; Zubrick SR; Verhulst FC. International comparisons of behavioral and emotional problems in preschool children: parents' reports from 24 societies. J Clin Child Adolesc Psychol. 2011, 40(3); 456-67.


Saavedra N; Fallard A; Araya M; Serón P; Lanas F; Salazar LA. Polimorfismo rs3091244 del gen de la proteína C reactiva influencia los niveles séricos de CRP-hs en individuos de la región de La Araucanía. Revista Chilena de Cardiología 2011, 30(1); 22 – 27.


Rubinstein AL; Irazola VE; Bazzano LA; Sobrino E; Calandrelli M; Lanas F; Lee AG; Manfredi JA; Olivera H; Ponzo J; Seron P; He J. Detection and follow-up of chronic obstructive pulmonary disease (COPD) and risk factors in the Southern Cone of Latin America: the pulmonary risk in South America (PRISA) study. BMC Pulm Med. 2011, 1; 11-34.


Yusuf S; Islam S; Chow CK; Rangarajan S; Dagenais G; Diaz R; Gupta R; Kelishadi R; Iqbal R; Avezum A; Kruger A; Kutty R; Lanas F; Lisheng L; Wei L; Lopez-Jaramillo P; Oguz A; Rahman O; Swidan H; Yusoff K; Zatonski W; Rosengren A; Teo KK; Prospective Urban Rural Epidemiology (PURE) Study Investigators. Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey. Lancet. 2011, 378(9798); 1231-1243.


Borie E; Fuentes R; Del Sol M; Oporto G; Engelke W. The influence of FDBA and autogenous bone particles on regeneration of calvaria defects in the rabbit: a pilot study. Ann Anat. 2011, 193(5):412-417.


Fuentes R; Oporto G; Olate S; Rojas Rauco M; Borie E; Engelke W. Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets. Int. J. Morphol. 2011, 29(1); 286-292.


Caamaño J; Saavedra N; Jaramillo PC; Lanas C; Lanas F; Salazar LA. TP53 codon 72 polymorphism is associated with coronary artery disease in Chilean subjects. Med Princ Pract. 2011, 20(2); 171-176.


Rosales A; Salazar LA. Efecto de variantes de los genes ABCB1 y CYP3A4 sobre la respuesta terapéutica a atorvastatina en individuos chilenos hipercolesterolémicos. Revista Chilena de Cardiología 2011, 30(2); 113-122.


Guzmán N; Salazar LA. Asociación de variantes funcionales en genes del metabolismo de la homocisteína con riesgo de trombosis venosa profunda e hiperhomocisteinemia en individuos del Sur de Chile. Revista Chilena de Cardiología 2011, 30(1); 28-32.


Do R; Xie C; Zhang X; Männistö S; Harald K; Islam S; Bailey SD; Rangarajan S; McQueen MJ; Diaz R; Lisheng L; Wang X; Silander K; Peltonen L; Yusuf S; Salomaa V; Engert JC; Anand SS; INTERHEART investigators. The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study. PLoS Med. 2011, 8(10); e1001106.


Granger CB; Alexander JH; McMurray JJ; Lopes RD; Hylek EM; Hanna M; Al-Khalidi HR; Ansell J; Atar D; Avezum A; Bahit MC; Diaz R; Easton JD; Ezekowitz JA; Flaker G; Garcia D; Geraldes M; Gersh BJ; Golitsyn S; Goto S; Hermosillo AG; Hohnloser SH; Horowitz J; Mohan P; Jansky P; Lewis BS; Lopez-Sendon JL; Pais P; Parkhomenko A; Verheugt FW; Zhu J; Wallentin L; ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011, 365(11); 981-992.


Patel MR; Mahaffey KW; Garg J; Pan G; Singer DE; Hacke W; Breithardt G; Halperin JL; Hankey GJ; Piccini JP; Becker RC; Nessel CC; Paolini JF; Berkowitz SD; Fox KA; Califf RM; ROCKET AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011, 365(10); 883-891.


Jolly SS; Yusuf S; Cairns J; Niemelä K; Xavier D; Widimsky P; Budaj A; Niemelä M; Valentin V; Lewis BS; Avezum A; Steg PG; Rao SV; Gao P; Afzal R; Joyner CD; Chrolavicius S; Mehta SR; RIVAL trial group. Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial. Lancet. 2011, 377(9775); 1409-1420.


ACTIVE I Investigators; Yusuf S; Healey JS; Pogue J; Chrolavicius S; Flather M; Hart RG; Hohnloser SH; Joyner CD; Pfeffer MA; Connolly SJ. Irbesartan in patients with atrial fibrillation. N Engl J Med. 2011, 364(10); 928-938.

 

2010

Seron P; Muñoz S; Lanas F. Levels of physical activity in an urban population from Temuco, Chile. Revista Medica de Chile 2010, 138(10); 1232-1239.


Guzman N; Lanas F; Salazar LA. Influence of Amerindian mitochondrial DNA haplogroups on thrombosis susceptibility and frequency of four genetic prothrombotic variants in Southern Chilean subjects. Clinica Chimica Acta 2010, 411(5-6); 444-447.


Guzman N; Salazar LA. Frequency of Prothrombotic Risk Factors in Patients with Deep Venous Thrombosis and Controls: Their Implications for Thrombophilia Screening in Chilean Subjects. Genetic Testing and Molecular Biomarkers 2010, 14(5); 599-602.


Herrera CL; Alvear M; Barrientos L; Montenegro G; Salazar LA. The antifungal effect of six commercial extracts of Chilean propolis on Candida spp. Ciencia e Investigacion Agraria 2010, 37(1);75-84.


Herrera CL; Fritz O; Montenegro G; Alvear M; del Sol M; Salazar LA. Propolis Decrease Diet-Induced Hepatic Steatosis in Mice. International Journal of Morphology 2010, 28(1); 75-84.


Hinuy HM; Hirata MH; Sampaio MF; Armaganijan D; Arazi SS; Salazar LA; Hirata RDC. Relationship between variants of the leptin gene and obesity and metabolic biomarkers in Brazilian individuals. Arquivos Brasileiros de Endocrinologia e Metabologia 2010, 54(3); 282-288.


Jaramillo PC; Lanas C; Lanas F; Salazar LA. Polymorphisms of the NOS3 gene in Southern Chilean subjects with coronary artery disease and controls. Clinica Chimica Acta 2010, 411(3-4); 258-262.


Salazar LA; Inostroza M; Jara C; Vega F; Garcia R; Ciuffardi I; Guzman N. Association of -765G > C polymorphism of the COX-2 gene with recurrent embryo implantation failure in Southern Chilean women. Clinica Chimica Acta 2010, 411(21-22); 1822-1824.


O'Donnell M; Xavier D; Diener C; Sacco R; Lisheng L; Zhang H; Pias P; Truelsen T; Chin SL; Rangarajan S; Devilliers L; Damasceno A; Mondo C; Lanas F; Avezum A; Diaz R; Varigos J; Hankey G; Teal P; Kapral M; Ryglewicz D; Czlonkowska A; Skowronska M; Lopez-Jaramillo P; Dans T; Langhorne P; Yusuf S; INTERSTROKE investigators. Rationale and design of INTERSTROKE: a global case-control study of risk factors for stroke. Neuroepidemiology. 2010, 35(1); 36-44.


Vilca F; Sanhueza A; Leiva V; Christakos G. An extended Birnbaum-Saunders model and its application in the study of environmental quality in Santiago, Chile. Stochastic Environmental Research and Risk Assessment 2010, 24(5); 771-782.


Ahmed SE; Castro-Kuriss C; Flores E; Leiva V; Sanhueza A. A Truncated Version of the Birnbaum-Saunders Distribution with an Application in Financial Risk. Pakistan Journal of Statistics 2010, 26(1); 293-311.


Balakrishnan N; Leiva V; Sanhueza A; Vilca F. Estimation in the Birnbaum-Saunders distribution based on scale-mixture of normals and the EM-algorithm. Sort-Statistics and Operations Research Transactions 2009, 33(2); 171-191. 



Kotz S; Leiva V; Sanhueza A. Two New Mixture Models Related to the Inverse Gaussian Distribution. Methodology and Computing in Applied Probability 2010, 12(1); 199-212.


Leiva V; Sanhueza A; Kotz S; Araneda N. A UNIFIED MIXTURE MODEL BASED ON THE INVERSE GAUSSIAN DISTRIBUTION. Pakistan Journal of Statistics 2010, 26(3); 445-460.


Leiva V; Sanhueza A; Sen PK; Araneda N. M-Procedures in the General Multivariate Nonlinear Regression Model. Pakistan Journal of Statistics 2010, 26(1); 1-13.


Leiva V; Vilca F; Balakrishnan N; Sanhueza A. A Skewed Sinh-Normal Distribution and Its Properties and Application to Air Pollution. Communications in Statistics-Theory and Methods 2010, 39(3); 426-443.


Manterola C; Vial M; Pineda V; Sanhueza A. Systematic Review of Literature with Different Types of Designs. International Journal of Morphology 2009, 27(4);1179-1186.


Manterola C; Vial M; Sanhueza A; Contreras J. Intrabiliary Rupture of Hepatic Echinococcosis, a Risk Factor for Developing Postoperative Morbidity: A Cohort Study. World Journal of Surgery 2010, 34(3); 581-586.


Vilca F; Sanhueza A; Leiva V; Christakos G. An extended Birnbaum-Saunders model and its application in the study of environmental quality in Santiago, Chile. Stochastic Environmental Research and Risk Assessment 2010, 24(5); 771-782.


Salazar LA; Gallardo N; Jara V; Torres D; Saavedra N; Jaramillo P; Caamaño J; Lanas C; Lanas F. Presencia del alelo T para el polimorfismo rs2781666 G>T del gen Arginasa 1 constituye un factor protector contra Enfermedad Arterial Coronaria. Revista Chilena de Cardiología 2010, 29(3); 316 – 321.


Cuevas A; Zambrano T; Márquez JL; Hernández A; Saavedra N; Jaramillo P; Caamaño J; Lanas C; Lanas F; Salazar LA. Polimorfismo SNP-43 del gen Calpaína- 10 en individuos con enfermedad coronaria y controles. Revista Chilena de Cardiología 2010, 29(2); 201 – 206.


Saavedra N; Cuevas A; Hernández A; Caamaño J; Jaramillo P; Lanas F; Salazar LA. Polimorfismos Genéticos De APOA5 se asocian a hipertrigliceridemia e hiperglicemia en individuos chilenos con enfermedad coronaria y controles. Revista Chilena de Cardiología 2010, 29(1); 19 – 27.


Salazar LA; Colivoro K; Díaz A; Sepúlveda S; Cuevas A; Saavedra N; Jaramillo P; Caamaño J; Lanas C; Lanas F. Asociación del polimorfismo RS2241766 del gen Adiponectina y Enfermedad Arterial Coronaria en individuos del Sur de Chile. Revista Chilena de Cardiología 2010, 29(2); 214 – 220.


Lagos J; Lemus J; Sierra F; Mella R; Fuentes F; Ocares G; Rosales A; Salazar LA; Durán D; Guzmán N. Asociación de niveles de lípidos y haplogrupos Amerindios de DNA mitocondrial en indivíduos Chilenos hipercolesterolémicos tratados con atorvastatina. Revista Chilena de Cardiología 2010, 29(2); 208-213.


Bhatt DL; Cryer BL; Contant CF; Cohen M; Lanas A; Schnitzer TJ; Shook TL; Lapuerta P; Goldsmith MA; Laine L; Scirica BM; Murphy SA; Cannon CP; COGENT Investigators. Clopidogrel with or without omeprazole in coronary artery disease. N Engl J Med. 2010, 363(20); 1909-1917.


CURRENT-OASIS 7 Investigators; Mehta SR; Bassand JP; Chrolavicius S; Diaz R; Eikelboom JW; Fox KA; Granger CB; Jolly S; Joyner CD; Rupprecht HJ; Widimsky P; Afzal R; Pogue J; Yusuf S. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. N Engl J Med. 2010, 363(10); 930-942.


Mehta SR; Tanguay JF; Eikelboom JW; Jolly SS; Joyner CD; Granger CB; Faxon DP; Rupprecht HJ; Budaj A; Avezum A; Widimsky P; Steg PG; Bassand JP; Montalescot G; Macaya C; Di Pasquale G; Niemela K; Ajani AE; White HD; Chrolavicius S; Gao P; Fox KA; Yusuf S; CURRENT-OASIS 7 trial investigators. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet. 2010, 376(9748); 1233-1243.


O'Donnell MJ; Xavier D; Liu L; Zhang H; Chin SL; Rao-Melacini P; Rangarajan S; Islam S; Pais P; McQueen MJ; Mondo C; Damasceno A; Lopez-Jaramillo P; Hankey GJ; Dans AL; Yusoff K; Truelsen T; Diener HC; Sacco RL; Ryglewicz D; Czlonkowska A; Weimar C; Wang X; Yusuf S; INTERSTROKE investigators. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet. 2010, 376(9735); 112-123.

 

2009

Caamaño J; Jaramillo PC; Lanas C; Lanas F; Salazar LA. Factor XII 46C -> T Gene Polymorphism in Chilean Subjects with Coronary Artery Disease and Controls. Medical Principles and Practice 2009, 18(2); 137-142.


Salazar LA; Medina F; Donoso F; Barrientos L; Sanhueza A. In vitro Antimicrobial Activity of Honey on mutans Streptococci. International Journal of Morphology 2009, 27(1); 77-82.


Balakrishnan N; Leiva V; Sanhueza A; Cabrera E. Mixture inverse Gaussian distributions and its transformations, moments and applications. Statistics 2009, 43(1); 91-104.


Garcia P; Manterola C; Araya JC; Villaseca M; Guzman P; Sanhueza A; Thomas M; Alvarez H; Roa JC. Promoter Methylation Profile in Preneoplastic and Neoplastic Gallbladder Lesions. Molecular Carcinogenesis 2009, 48(1); 79-89.


Leiva V; Sanhueza A; Angulo J. A length-biased version of the Birnbaum-Saunders distribution with application in water quality. Stochastic Environmental Research and Risk Assessment 2009, 23(3); 299-307.


Leiva V; Sanhueza A; Kelmansky DM; Martinez EJ. On the glog-normal distribution and its application to the gene expression problem. Computational Statistics & Data Analysis 2009, 53(5); 1613-1621.


Losada H; Manterola C; Pineda V; Vial M; Sanhueza A. Design of a methodological quality scale for prognostic studies. Revista Chilena de Cirugia 2009, 61(1); 59-72.


Manterola C; Pineda V; Vial M; Sanhueza A. Randomized clinical trials in surgery. Revista Chilena de Cirugia 2009, 61(5); 482-489.


Manterola C; Sanhueza A; Vial M; Moraga J. Liver abscess of hydatid origin as a risk factor for postoperative complications in hydatidosis. Revista Chilena de Cirugia 2009, 61(4); 333-338.


Sanhueza A; Leiva V; Flores E. On a length-biased life distribution based on the sinh-normal model. Journal of the Korean Statistical Society 2009, 38(4); 323-330.


Sepulveda G; Espindola M; Maureira M; Sepulveda E; Fernandez JI; Oliva C; Sanhueza A. Negative-pressure wound therapy versus standard wound dressing in the treatment of diabetic foot amputation. A randomised controlled trial. Cirugia Espanola 2009, 86(3); 171-177.


Torres-Quevedo R; Manterola C; Sanhueza A; Bustos L; Pineda V; Vial M. Diagnostic properties of a symptoms scale for diagnosing reflux esophagitis. Journal of Clinical Epidemiology 2009, 62(1); 97-101.


Konstam MA; Neaton JD; Dickstein K; Drexler H; Komajda M; Martinez FA; Riegger GA; Malbecq W; Smith RD; Guptha S; Poole-Wilson PA; HEAAL Investigators. Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial. Lancet 2009, 374(9704); 1840-1848.


Mehta SR; Granger CB; Boden WE; Steg PG; Bassand JP; Faxon DP; Afzal R; Chrolavicius S; Jolly SS; Widimsky P; Avezum A; Rupprecht HJ; Zhu J; Col J; Natarajan MK; Horsman C; Fox KA; Yusuf S; TIMACS Investigators. Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med. 2009, 360(21); 2165-2175.


ACTIVE Investigators; Connolly SJ; Pogue J; Hart RG; Hohnloser SH; Pfeffer M; Chrolavicius S; Yusuf S. Effect of clopidogrel added to aspirin in patients with atrial fibrillation. N Engl J Med. 2009, 360(20); 2066-2078.


Hohnloser SH; Crijns HJ; van Eickels M; Gaudin C; Page RL; Torp-Pedersen C; Connolly SJ; ATHENA Investigators. Effect of dronedarone on cardiovascular events in atrial fibrillation. N Engl J Med. 2009, 360(7); 668-678.


Tardif JC; Ponikowski P; Kahan T; ASSOCIATE Study Investigators. Efficacy of the I(f) current inhibitor ivabradine in patients with chronic stable angina receiving beta-blocker therapy: a 4-month, randomized, placebo-controlled trial. Eur Heart J, 30(5); 540-548.


Caamaño J; Saavedra N; Jaramillo P; Lanas C; Lanas F; Salazar LA. Polimorfismo Pro72Arg del gen TP53 se asocia a enfermedad coronaria en individuos Chilenos. Revista Chilena de Cardiología 2009, 28(2); 151-157.


Márquez JL; Salazar LA. Influencia epigenómica de la actividad/inactividad física en el origen de la Diabetes mellitus tipo 2. Revista Internacional de Ciencias del Deporte 2009, V; 1-20